Meat physiology, stress, and degenerative physiology

ARTICLE | Ray Peat

Tue Nov 08 09:17:41 MST 2016 | null


The US Department of Agriculture claims that the Pure Food and Drugs Act of 1906 and the Meat Inspection Act of the same year were passed because the food industry demanded them. Ordinary historians believe that Upton Sinclair's 1905 serial publication of his novel about the meat industry, The Jungle, caused the public and Theodore Roosevelt to pressure Congress to pass the laws. Sinclair's


Fatigue, aging, and recuperation

ARTICLE | Ray Peat

Tue Nov 08 09:14:21 MST 2016 | null


- Old people and sick people tire easily. Surprisingly, little is known to explain that common fact. - Myths about lactic acid and oxygen debt have misdirected most fatigue research. - The cellular processes involved in fatigue overlap with those of aging. - Knowledge about the mechanisms of fatigue should be useful in preventing some tissue swelling disorders, organ failure, degenerative


Cataracts: water, energy, light, and aging

ARTICLE | Ray Peat

Tue Nov 08 09:12:42 MST 2016 | null


Because of the baby boom population bulge, the market for cataract surgery and the little plastic intraocular lenses is growing wonderfully. According to the World Health Organization, there were about 20 million cataract surgeries performed in 2010, with 32 million expected in 2020. In the US, about 3 million cataract surgeries are performed annually. Revenue from sale of the intraocular lenses


Serotonin: Effects in disease, aging and inflammation

ARTICLE | Ray Peat

Tue Nov 08 09:11:50 MST 2016 | null


Interpreting medical publications requires some skills that aren't needed for understanding more strictly scientific reports, because medical writing often takes into account the fact that physicians spend most of their time interacting with the public, rather than studying. The public's understanding of medicine is shaped by "public relations," by the introduction of words and concepts that frame


The Cancer Matrix

ARTICLE | Ray Peat

Tue Nov 08 09:10:59 MST 2016 | null


It isn't hard to understand that in heart failure the heart is undergoing changes in a unitary way, with all parts of the organ affected, and that parallel changes are happening in the rest of the body, interacting with and contributing to the changes in the heart, so that heart failure is now considered to be a systemic disease. (Most doctors see the systemic nature of heart disease, at least to


Heart and hormones

ARTICLE | Ray Peat

Tue Nov 08 09:10:00 MST 2016 | null


The heart's unique behavior has given cardiologists a particularly mechanical perspective on biology. If a cardiologist and an oncologist have anything to talk about, it's likely to be about why cancer treatments cause heart failure; a cardiologist and an endocrinologist might share an interest in "cardioprotective estrogen" and "cardiotoxic obesity." Cell physiology and bioenergetics aren't


Mitonchondria and mortality:

ARTICLE | Ray Peat

Tue Nov 08 09:09:07 MST 2016 | null


Diet, exercise, and medicine, damaging or repairing respiratory metabolism MAIN IDEAS AND CONTEXTS Lactic acid and carbon dioxide have opposing effects. Intense exercise damages cells in ways that cumulatively impair metabolism. There is clear evidence that glycolysis, producing lactic acid from glucose, has toxic effects, suppressing respiration and killing cells. Within five minutes


Physiology texts and the real world

ARTICLE | Ray Peat

Tue Nov 08 09:06:57 MST 2016 | null


Hospital accidents kill more people than highway accidents. But when people die while they are receiving standard, but irrational and antiscientific treatments and “support,” the deaths aren’t counted as accidents. The numbers are large. Medical training and medical textbooks bear great responsibility for those unnecessary deaths. Most medical research is done under the influence of mistaken


The dark side of stress (learned helplessness)

ARTICLE | Ray Peat

Tue Nov 08 09:05:35 MST 2016 | null


Acetylcholine is the "neurotransmitter" of cholinergic nerves, including the parasympathetic system. Cholinesterase (or acetylcholinesterase) is an enzyme that destroys acetylcholine, limiting the action of the cholinergic nerves. Attaching a phosphate group to the cholinesterase enzyme inactivates it, prolonging and intensifying the action of cholinergic stimulation


Membranes schmembranes a Living bio-energetic cellular physiology

ARTICLE | Pranarupa

Mon Nov 07 23:58:29 MST 2016 | null

“Then tell me, what is the material world, and is it dead?” He, laughing. answer’d: “I will write a book on leaves of flowers, if you will feed me on love thoughts & give me now and then A cup of sparkling poetic fancies; so, when I am tipsie, I’ll sing to you to this soft lute, and shew you all alive The world, where every particle of dust breathes forth its joy.” -William Blake The cell