ARTICLE | Ray Peat

null | Aging, estrogen, and progesterone


“Estrogen” refers not just to a family of steroids but to a class of substances that can produce approximately the same effects as estradiol and its metabolites. Even before the pure substance was isolated in the 1930s, the effects of fluid from ovarian follicles were studied. It was soon discovered that many chemicals could produce similar effects. By the middle of the century, many toxic


ARTICLE | Ray Peat

null | RU486, Cancer, Estrogen, and Progesterone.


Recently many people have been disturbed by reading claims that progesterone can cause cancer, or diabetes, or autoimmune diseases, or heart disease, or Alzheimer's disease. A flurry of press conferences, and a few groups of "molecular biologists" working on "progesterone receptors," and the results of studies in which Prempro (containing a synthetic "progestin") increased breast cancer, have


ARTICLE | Ray Peat

null | Caffeine: A vitamin-like nutrient, or adaptogen


Questions about tea and coffee, cancer and other degenerative diseases, and the hormones. There is a popular health-culture that circulates mistaken ideas about nutrition, and coffee drinking has been a perennial target of this culture. It is commonly said that coffee is a drug, not a food, and that its drug action is harmful, and that this harm is not compensated by any nutritional benefit


ARTICLE | Ray Peat

null | Unsaturated Vegetable Oils: Toxic


GLOSSARY: Immunodeficiency (weakness of the immune system) can take many forms. AIDS, for example, refers to an immunodeficiency which is "acquired," rather than "inborn." Radiation and vegetable oils can cause "acquired immunodeficiency." Unsaturated oils, especially polyunsaturates, weaken the immune system's function in ways that are similar to the damage caused by radiation, hormone


ARTICLE | Andrew Kim

null | Fructose is > glucose Part IV

Since the 1970s the availability and consumption of high fructose corn syrup (HFCS) increased considerably, while sucrose – from sugar cane and beets – decreased by about the same amount. Overall, however, the caloric intake of sugars from all added sources decreased subtly, as did the consumption of fruits and vegetables, which are additional natural sources of sugars. It should be noted that


ARTICLE | Andrew Kim

null | Insulin revisited, cell physiology, membrane pumps, and internet commenters

In my first “fact check” of Dr. Ray Peat, I had discussed the mechanisms by which insulin exerts its effects from the conventional textbook point-of-view. I’ve gotten mostly good feedback on that post, and some idiotic ones, from the people who obviously didn’t take the time to read it, or if they did, failed to understand it. Briefly, the conventional view is that insulin, upon being


ARTICLE | Andrew Kim

null | Protective inhibition, energy generation, and the neuroprotective effects of ATP

Terminology Axon:the slender part of a neuron that conducts electrical impulses away from the neuron’s cell body. Autonomicganglia: a cluster of neurons that provides a junction between the autonomic nerves originating from the brain and spinal cord, with those supplying tissues in the body. Glial cells: non-neuronal cells that provide support to neurons by, for instance, producing myelin


ARTICLE | Andrew Kim

null | Dr. Ray Peat Fact Check 1: Insulin's Role in Blood Glucose Regulation

"Insulin is important in the regulation of blood sugar, but its importance has been exaggerated because of the diabetes/insulin industry. Insulin itself has been found to account for only about 8% of the "insulin-like activity" of the blood, with potassium being probably the largest factor. There probably isn't any process in the body that doesn't potentially affect blood sugar." -Dr. Ray Peat


ARTICLE | Andrew Kim

null | Why cells go bad: a new appreciation and understanding of ATP opens up an untapped avenue for fighting diabetes, cancer, aging, etc.

It’s refreshing to see people beginning to think clearly and rationally and move away from gimmicky diets that have little basis in fact, reality, or objectivity, and to ones that are firmly seated in all aspects of human physiology and science. After all, this is why most of us choose to eat a certain way, that is to be as healthy as we can be, both physically and mentally . . . not to, say


ARTICLE | Andrew Kim

null | Preserving Brain Function: Principles, Pitfalls, and Practical Conclusions

INTRODUCTION I recently had the opportunity to attend a physician-only-lecture at a hospital about the use of ketogenic diets for the treatment of epilepsy in children. If you at least casually follow the discourse on this dietary approach on the interwebz, especially with regard to the interest of effecting cures, you’d probably think that not only should all children with epilepsy be placed


ARTICLE | Andrew Kim

null | My Guest Post for 180 Degree Health

Hey guys, My first guest post for Matt Stone's site went live today. Here is a direct link: Gram Negative Bacteria and Obesity If you don't know, Matt, who I've been in communication with for a few months now, runs a really interesting site where there's no dogma or rigid mindedness allowed. Matt is open-minded, highly eager to continuously learn, and not afraid to make mistakes


ARTICLE | Andrew Kim

null | An Examination of Popular "Diets" -- Avoid Them All

Some of the dietary practices that are currently promoted have the inconvenience of producing some of the effects that these practices are being undertaken to check in the first place—namely cortisol and estrogen. If any person were so persuaded to do so, he or she should bear in mind that a deficiency of calories, carbohydrate, salt, calcium, and excessive amounts of histamine, choline, and